Inositol
Inositol is part of the vitamin B complex. It promotes healthy brain development and function, and works closely with choline to move fats out of the heart and liver. Inositol is also vital for hair growth, and, as a component of lecithin, helps to prevent high cholesterol and the hardening of the arteries caused by cholesterol buildup. It has also been said to have a calming effect on the nervous system, and is being studied as a possible treatment for depression, panic attacks, and even Alzheimer’s disease.
How does the body produce its own supply of inositol? Bacteria in the intestines convert the phytic acid found in plant fibers into inositol, so the body is able to manufacture its own supply of this substance. Inositol is also found in a variety of foods containing myo-inositol, such as cantaloupe, citrus fruits (other than lemons), nuts, oats, rice, beans, chickpeas, liver, pork, veal, whole grains, lecithin granules, and wheat germ.
Inositol plays an important part in the health of cell membranes especially the specialized cells in the brain, bone marrow, eyes and intestines. The function of the cell membranes is to regulate the contents of the cells, which makes effective functioning possible.
Inositol is said to promote healthy hair, hair growth, and helps in controlling estrogen levels and may assist in preventing breast lumps.
It may also be of benefit in reducing blood cholesterol levels.
Deficiency of inositol
If your intake is not sufficient, you may experience symptoms such as eczema, hair loss, constipation, and abnormalities of the eyes and raised cholesterol.
Dosage
The dosage underneath is the Recommended Dietary Allowance (RDA), but be aware that this dosage is the minimum that you require per day, to ward off serious deficiency of this particular nutrient. In the therapeutic use of this nutrient, the dosage is usually increased considerably, but the toxicity level must be kept in mind.
Supplementation is usually 100 mg per day.
Toxicity and symptoms of high intake
No toxic effects known, but diarrhea has been noted with the intake of very high dosage of inositol.
Best used with
Choline should be taken in the same amount as inositol and the best is to take the entire B group vitamins with it, Vitamin E, vitamin C as well as folic acid and linoleic acid is thought to increase the functioning of inositol.
When more inositol may be required
Taking of long term antibiotics may increase your need for inositol, as well as if you consume a lot of coffee.
Enemy of inositol
Coffee kills this nutrient.
Food sources
Inositol is available from both plant and animal sources. The plant form in which inositol is available is phytic acid, which can bind with minerals and so affect their absorption negatively.
Inositol phosphates have anticancer function.
The body is also able to manufacture this factor. Inositol is available from wheat germ, brewers yeast. bananas, liver, brown rice, oat flakes, nuts, unrefined molasses, raisins and vegetables.
Inositol hexaphosphate (InsP6, phytic acid) is ubiquitous in the plant kingdom and is abundant in cereals and legumes. In much smaller amounts InsP6 and its lower phosphorylated forms (InsP1-5) are contained in most mammalian cells, where they are important in regulating vital cellular functions. Both in vivo and in vitro experiments have suggested striking anticancer potential (preventive as well as therapeutic) for InsP6 with and without inositol. In addition to reduce cell proliferation, InsP6 increases differentiation of malignant cells often resulting in reversion to the normal phenotype. InsP6 is quickly absorbed from the rat stomach and upper intestine and distributed as inositol and InsP1. In vitro it is instantaneously taken up by malignant cells undergoing variable dephosphorylation to inositol and InsP1-5, pointing toward their role in mediating the action of InsP6. Because InsP6 is high in high-fiber diets, our studies also may explain, at least in part, the epidemiologic observation showing high-fiber diets are associated with a lower incidence of certain cancers. Although further studies are needed to elucidate the mechanism(s) of this action, inclusion of InsP6 in our strategies for cancer prevention and therapy is warranted.
1. Relief from depression.
2. Relief from panic attacks.
3. Relief from OCD.
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